diff --git a/CHANGELOG.md b/CHANGELOG.md
index eb6b62623b..dcd9cbdabd 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -23,6 +23,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - Fixed Pretty measure not respecting expand_all https://github.com/Textualize/rich/issues/1998
 - Collapsed definitions for single-character spinners, to save memory and reduce import time.
 - Fix print_json indent type in __init__.py
+- Fix error when inspecting object defined in REPL https://github.com/Textualize/rich/pull/2037
 
 ### Changed
 
diff --git a/rich/_inspect.py b/rich/_inspect.py
index b3652bfbdb..01713e5767 100644
--- a/rich/_inspect.py
+++ b/rich/_inspect.py
@@ -98,7 +98,8 @@ def _get_signature(self, name: str, obj: Any) -> Optional[Text]:
         source_filename: Optional[str] = None
         try:
             source_filename = getfile(obj)
-        except TypeError:
+        except (OSError, TypeError):
+            # OSError is raised if obj has no source file, e.g. when defined in REPL.
             pass
 
         callable_name = Text(name, style="inspect.callable")