diff --git a/.github/workflows/end-to-end-tests.yml b/.github/workflows/end-to-end-tests.yml
new file mode 100644
index 00000000..64cf4b12
--- /dev/null
+++ b/.github/workflows/end-to-end-tests.yml
@@ -0,0 +1,35 @@
+name: End-to-end Tests
+
+on:
+  push:
+    branches:
+      - main
+  pull_request:
+
+jobs:
+  test:
+    name: End-to-end Tests
+    runs-on: ubuntu-latest
+    timeout-minutes: 20
+
+    steps:
+      - name: Checkout repository
+        uses: actions/checkout@v4
+
+      - name: Set up Docker Buildx
+        uses: docker/setup-buildx-action@v3
+
+      - name: Set UID and GID for PHP in WordPress images
+        run: |
+          echo "PHP_FPM_UID=$(id -u)" >> $GITHUB_ENV
+          echo "PHP_FPM_GID=$(id -g)" >> $GITHUB_ENV
+
+      - name: Install Playwright browsers
+        run: npx playwright install --with-deps
+
+      - name: Run end-to-end tests
+        run: composer run test-e2e
+
+      - name: Stop Docker containers
+        if: always()
+        run: composer run wp-test-clean
diff --git a/.github/workflows/wp-tests-end-to-end.yml b/.github/workflows/wp-tests-end-to-end.yml
new file mode 100644
index 00000000..2b32a5a0
--- /dev/null
+++ b/.github/workflows/wp-tests-end-to-end.yml
@@ -0,0 +1,35 @@
+name: WordPress End-to-end Tests
+
+on:
+  push:
+    branches:
+      - main
+  pull_request:
+
+jobs:
+  test:
+    name: WordPress End-to-end Tests
+    runs-on: ubuntu-latest
+    timeout-minutes: 20
+
+    steps:
+      - name: Checkout repository
+        uses: actions/checkout@v4
+
+      - name: Set up Docker Buildx
+        uses: docker/setup-buildx-action@v3
+
+      - name: Set UID and GID for PHP in WordPress images
+        run: |
+          echo "PHP_FPM_UID=$(id -u)" >> $GITHUB_ENV
+          echo "PHP_FPM_GID=$(id -g)" >> $GITHUB_ENV
+
+      - name: Install Playwright browsers
+        run: npx playwright install --with-deps
+
+      - name: Run WordPress end-to-end tests
+        run: composer run wp-test-e2e
+
+      - name: Stop Docker containers
+        if: always()
+        run: composer run wp-test-clean
diff --git a/.github/workflows/wp-tests-phpunit-run.js b/.github/workflows/wp-tests-phpunit-run.js
index ff4d873c..03ce2697 100644
--- a/.github/workflows/wp-tests-phpunit-run.js
+++ b/.github/workflows/wp-tests-phpunit-run.js
@@ -1,5 +1,5 @@
 /*
- * Wrap the "composer run wp-tests-phpunit" command to process tests
+ * Wrap the "composer run wp-tests-php" command to process tests
  * that are expected to error and fail at the moment.
  *
  * This makes sure that the CI job passes, while explicitly tracking
@@ -108,7 +108,7 @@ console.log( 'Expected failures:', expectedFailures );
 try {
 	try {
 		execSync(
-			`composer run wp-test-phpunit -- --log-junit=phpunit-results.xml --verbose`,
+			`composer run wp-test-php -- --log-junit=phpunit-results.xml --verbose`,
 			{ stdio: 'inherit' }
 		);
 		console.log( '\n⚠️ All tests passed, checking if expected errors/failures occurred...' );
diff --git a/.github/workflows/wp-tests-phpunit.yml b/.github/workflows/wp-tests-phpunit.yml
index 0bf5c511..d2746fdc 100644
--- a/.github/workflows/wp-tests-phpunit.yml
+++ b/.github/workflows/wp-tests-phpunit.yml
@@ -1,4 +1,4 @@
-name: WordPress Tests
+name: WordPress PHPUnit Tests
 
 on:
   push:
@@ -24,12 +24,6 @@ jobs:
           echo "PHP_FPM_UID=$(id -u)" >> $GITHUB_ENV
           echo "PHP_FPM_GID=$(id -g)" >> $GITHUB_ENV
 
-      - name: Setup WordPress test environment
-        run: composer run wp-setup
-
-      - name: Start WordPress test environment
-        run: composer run wp-test-start
-
       - name: Run WordPress PHPUnit tests
         run: node .github/workflows/wp-tests-phpunit-run.js
 
diff --git a/composer.json b/composer.json
index 1d27a626..4ac7fc76 100644
--- a/composer.json
+++ b/composer.json
@@ -39,6 +39,13 @@
 		"test": [
 			"phpunit"
 		],
+		"test-e2e": [
+			"@wp-test-ensure-env @no_additional_args",
+			"rm -f tests/e2e/package.json tests/e2e/node_modules @no_additional_args",
+			"ln -s ../../wordpress/package.json tests/e2e/package.json @no_additional_args",
+			"ln -s ../../wordpress/node_modules tests/e2e/node_modules @no_additional_args",
+			"npm --prefix tests/e2e run test:e2e -- --config . @additional_args"
+		],
 		"wp-setup": [
 			"./wp-setup.sh"
 		],
@@ -47,13 +54,27 @@
 		],
 		"wp-test-start": [
 			"npm --prefix wordpress run env:start",
-			"npm --prefix wordpress run env:install"
+			"npm --prefix wordpress run env:install",
+			"npm --prefix wordpress run env:cli -- plugin install gutenberg",
+			"npm --prefix wordpress run env:cli -- plugin install query-monitor"
+		],
+		"wp-test-ensure-env": [
+			"if [ ! -f wordpress/src/wp-load.php ]; then composer run wp-setup; fi",
+			"@putenv COMPOSE_IGNORE_ORPHANS=true",
+			"cd wordpress && if [ -z \"$(node tools/local-env/scripts/docker.js ps -q)\" ]; then cd ..; composer run wp-test-start; fi"
+		],
+		"wp-test-php": [
+			"@wp-test-ensure-env @no_additional_args",
+			"rm -rf wordpress/src/wp-content/database/.ht.sqlite @no_additional_args",
+			"npm --prefix wordpress run test:php -- @additional_args"
 		],
-		"wp-test-phpunit": [
-			"rm -rf wordpress/src/wp-content/database && npm --prefix wordpress run test:php --"
+		"wp-test-e2e": [
+			"@wp-test-ensure-env @no_additional_args",
+			"npm --prefix wordpress run test:e2e -- @additional_args"
 		],
 		"wp-test-clean": [
-			"npm --prefix wordpress run env:clean"
+			"npm --prefix wordpress run env:clean",
+			"rm -rf wordpress/src/wp-content/database/.ht.sqlite"
 		]
 	}
 }
diff --git a/tests/e2e/.gitignore b/tests/e2e/.gitignore
new file mode 100644
index 00000000..a5dd015f
--- /dev/null
+++ b/tests/e2e/.gitignore
@@ -0,0 +1,3 @@
+/artifacts
+/node_modules
+/package.json
diff --git a/tests/e2e/playwright.config.js b/tests/e2e/playwright.config.js
new file mode 100644
index 00000000..531b6a1d
--- /dev/null
+++ b/tests/e2e/playwright.config.js
@@ -0,0 +1,27 @@
+/**
+ * External dependencies
+ */
+import path from 'node:path';
+import { defineConfig } from '@playwright/test';
+
+/**
+ * WordPress dependencies
+ */
+const baseConfig = require( '@wordpress/scripts/config/playwright.config' );
+
+process.env.WP_ARTIFACTS_PATH ??= path.join( process.cwd(), 'artifacts' );
+process.env.STORAGE_STATE_PATH ??= path.join(
+	process.env.WP_ARTIFACTS_PATH,
+	'storage-states/admin.json'
+);
+
+const config = defineConfig( {
+	...baseConfig,
+	globalSetup: require.resolve( '../../wordpress/tests/e2e/config/global-setup.js' ),
+	webServer: {
+		...baseConfig.webServer,
+		command: 'npm run env:start',
+	},
+} );
+
+export default config;
diff --git a/tests/e2e/specs/query-monitor-plugin.test.js b/tests/e2e/specs/query-monitor-plugin.test.js
new file mode 100644
index 00000000..64b13213
--- /dev/null
+++ b/tests/e2e/specs/query-monitor-plugin.test.js
@@ -0,0 +1,47 @@
+/**
+ * WordPress dependencies
+ */
+import { test, expect } from '@wordpress/e2e-test-utils-playwright';
+
+test.describe( 'Query Monitor plugin', () => {
+	async function deactivateQueryMonitor( requestUtils ) {
+		await requestUtils.deactivatePlugin( 'query-monitor' );
+		const plugin = await requestUtils.rest( {
+			path: 'wp/v2/plugins/query-monitor/query-monitor',
+		} );
+		expect( plugin.status ).toBe( 'inactive' );
+	}
+
+	test.beforeEach( async ( { requestUtils }) => {
+		await deactivateQueryMonitor( requestUtils );
+	} );
+
+	test.afterEach( async ( { requestUtils }) => {
+		await deactivateQueryMonitor( requestUtils );
+	} );
+
+	test( 'should activate', async ( { admin, page } ) => {
+		// Activate the Query Monitor plugin on the plugins page.
+		await admin.visitAdminPage( '/plugins.php' );
+		await page.getByLabel( 'Activate Query Monitor', { exact: true } ).click();
+		await page.getByText( 'Plugin activated.', { exact: true } ).waitFor();
+
+		// Click on the Query Monitor menu item in the WordPress admin bar.
+		await page.locator('a[role="menuitem"][href="#qm-overview"][aria-expanded="false"]').click();
+
+		// Wait for the Query Monitor panel to open.
+		await page.locator( '#query-monitor-main' ).waitFor();
+		await page.getByRole( 'heading', { name: 'Query Monitor', exact: true } ).waitFor();
+
+		// Click on the Database Queries tab.
+		await page.getByRole( 'tab', { name: 'Database Queries' } ).click();
+
+		// Verify the first logged query.
+		const sqlCell = page.locator( '.qm-row-sql' ).first();
+		await expect( sqlCell ).toContainText( 'SELECT option_name, option_value' );
+
+		// Check that the query is logged with SQLite information.
+		await sqlCell.getByLabel( 'Toggle SQLite queries' ).click();
+		expect( page.locator('.qm-sqlite-query', { hasText: 'SELECT `option_name` , `option_value` FROM `wp_options`' }).first() ).toBeVisible();
+	} );
+} );
diff --git a/wp-setup.sh b/wp-setup.sh
index b3e00de7..44b8c016 100755
--- a/wp-setup.sh
+++ b/wp-setup.sh
@@ -65,3 +65,4 @@ sed -i.bak "s#class WpdbExposedMethodsForTesting extends wpdb {#class WpdbExpose
 # 6. Install dependencies.
 echo "Installing dependencies..."
 npm --prefix "$WP_DIR" install
+npm --prefix "$WP_DIR" run build:dev