diff --git a/src/wp-includes/blocks.php b/src/wp-includes/blocks.php
index 591a7971cafb0..431e2b015332c 100644
--- a/src/wp-includes/blocks.php
+++ b/src/wp-includes/blocks.php
@@ -757,6 +757,38 @@ function get_hooked_blocks() {
 	return $hooked_blocks;
 }
 
+/**
+ * Conditionally returns the markup for a given hooked block type.
+ *
+ * Accepts two arguments: A reference to an anchor block, and the name of a hooked block type.
+ * If the anchor block has already been processed, and the given hooked block type is in the list
+ * of ignored hooked blocks, an empty string is returned.
+ *
+ * This function is meant for internal use only.
+ *
+ * @since 6.5.0
+ * @access private
+ *
+ * @param array   $anchor_block      The anchor block. Passed by reference.
+ * @param string  $hooked_block_type The name of the hooked block type.
+ * @return string The markup for the given hooked block type, or an empty string if the block is ignored.
+ */
+function get_hooked_block_markup( &$anchor_block, $hooked_block_type ) {
+	if ( ! isset( $anchor_block['attrs']['metadata']['ignoredHookedBlocks'] ) ) {
+		$anchor_block['attrs']['metadata']['ignoredHookedBlocks'] = array();
+	}
+
+	if ( in_array( $hooked_block_type, $anchor_block['attrs']['metadata']['ignoredHookedBlocks'] ) ) {
+		return '';
+	}
+
+	// The following is only needed for the REST API endpoint.
+	// However, its presence does not affect the frontend.
+	$anchor_block['attrs']['metadata']['ignoredHookedBlocks'][] = $hooked_block_type;
+
+	return get_comment_delimited_block_content( $hooked_block_type, array(), '' );
+}
+
 /**
  * Returns a function that injects the theme attribute into, and hooked blocks before, a given block.
  *
@@ -813,7 +845,7 @@ function make_before_block_visitor( $hooked_blocks, $context ) {
 			 */
 			$hooked_block_types = apply_filters( 'hooked_block_types', $hooked_block_types, $relative_position, $anchor_block_type, $context );
 			foreach ( $hooked_block_types as $hooked_block_type ) {
-				$markup .= get_comment_delimited_block_content( $hooked_block_type, array(), '' );
+				$markup .= get_hooked_block_markup( $parent_block, $hooked_block_type );
 			}
 		}
 
@@ -826,7 +858,7 @@ function make_before_block_visitor( $hooked_blocks, $context ) {
 		/** This filter is documented in wp-includes/blocks.php */
 		$hooked_block_types = apply_filters( 'hooked_block_types', $hooked_block_types, $relative_position, $anchor_block_type, $context );
 		foreach ( $hooked_block_types as $hooked_block_type ) {
-			$markup .= get_comment_delimited_block_content( $hooked_block_type, array(), '' );
+			$markup .= get_hooked_block_markup( $block, $hooked_block_type );
 		}
 
 		return $markup;
@@ -874,7 +906,7 @@ function make_after_block_visitor( $hooked_blocks, $context ) {
 		/** This filter is documented in wp-includes/blocks.php */
 		$hooked_block_types = apply_filters( 'hooked_block_types', $hooked_block_types, $relative_position, $anchor_block_type, $context );
 		foreach ( $hooked_block_types as $hooked_block_type ) {
-			$markup .= get_comment_delimited_block_content( $hooked_block_type, array(), '' );
+			$markup .= get_hooked_block_markup( $block, $hooked_block_type );
 		}
 
 		if ( $parent_block && ! $next ) {
@@ -888,7 +920,7 @@ function make_after_block_visitor( $hooked_blocks, $context ) {
 			/** This filter is documented in wp-includes/blocks.php */
 			$hooked_block_types = apply_filters( 'hooked_block_types', $hooked_block_types, $relative_position, $anchor_block_type, $context );
 			foreach ( $hooked_block_types as $hooked_block_type ) {
-				$markup .= get_comment_delimited_block_content( $hooked_block_type, array(), '' );
+				$markup .= get_hooked_block_markup( $parent_block, $hooked_block_type );
 			}
 		}
 
diff --git a/tests/phpunit/tests/blocks/getHookedBlockMarkup.php b/tests/phpunit/tests/blocks/getHookedBlockMarkup.php
new file mode 100644
index 0000000000000..918ad97031e2e
--- /dev/null
+++ b/tests/phpunit/tests/blocks/getHookedBlockMarkup.php
@@ -0,0 +1,68 @@
+<?php
+/**
+ * Tests for the get_hooked_block_markup function.
+ *
+ * @package WordPress
+ * @subpackage Blocks
+ *
+ * @since 6.5.0
+ *
+ * @group blocks
+ * @group block-hooks
+ */
+class Tests_Blocks_GetHookedBlockMarkup extends WP_UnitTestCase {
+	/**
+	 * @ticket 59646
+	 *
+	 * @covers ::get_hooked_block_markup
+	 */
+	public function test_get_hooked_block_markup_adds_metadata() {
+		$anchor_block = array(
+			'blockName' => 'tests/anchor-block',
+		);
+
+		$actual = get_hooked_block_markup( $anchor_block, 'tests/hooked-block' );
+		$this->assertSame( array( 'tests/hooked-block' ), $anchor_block['attrs']['metadata']['ignoredHookedBlocks'] );
+		$this->assertSame( '<!-- wp:tests/hooked-block /-->', $actual );
+	}
+
+	/**
+	 * @ticket 59646
+	 *
+	 * @covers ::get_hooked_block_markup
+	 */
+	public function test_get_hooked_block_markup_if_block_is_already_hooked() {
+		$anchor_block = array(
+			'blockName' => 'tests/anchor-block',
+			'attrs'     => array(
+				'metadata' => array(
+					'ignoredHookedBlocks' => array( 'tests/hooked-block' ),
+				),
+			),
+		);
+
+		$actual = get_hooked_block_markup( $anchor_block, 'tests/hooked-block' );
+		$this->assertSame( array( 'tests/hooked-block' ), $anchor_block['attrs']['metadata']['ignoredHookedBlocks'] );
+		$this->assertSame( '', $actual );
+	}
+
+	/**
+	 * @ticket 59646
+	 *
+	 * @covers ::get_hooked_block_markup
+	 */
+	public function test_get_hooked_block_markup_adds_to_ignored_hooked_blocks() {
+		$anchor_block = array(
+			'blockName' => 'tests/anchor-block',
+			'attrs'     => array(
+				'metadata' => array(
+					'ignoredHookedBlocks' => array( 'tests/hooked-block' ),
+				),
+			),
+		);
+
+		$actual = get_hooked_block_markup( $anchor_block, 'tests/other-hooked-block' );
+		$this->assertSame( array( 'tests/hooked-block', 'tests/other-hooked-block' ), $anchor_block['attrs']['metadata']['ignoredHookedBlocks'] );
+		$this->assertSame( '<!-- wp:tests/other-hooked-block /-->', $actual );
+	}
+}
diff --git a/tests/phpunit/tests/blocks/getHookedBlocks.php b/tests/phpunit/tests/blocks/getHookedBlocks.php
index 4052e2a36fe36..66a9e00efea69 100644
--- a/tests/phpunit/tests/blocks/getHookedBlocks.php
+++ b/tests/phpunit/tests/blocks/getHookedBlocks.php
@@ -149,7 +149,7 @@ public function test_loading_template_with_hooked_blocks() {
 			$template->content
 		);
 		$this->assertStringContainsString(
-			'<!-- wp:post-content {"layout":{"type":"constrained"}} /-->'
+			'<!-- wp:post-content {"layout":{"type":"constrained"},"metadata":{"ignoredHookedBlocks":["tests/hooked-after"]}} /-->'
 			. '<!-- wp:tests/hooked-after /-->',
 			$template->content
 		);
@@ -176,7 +176,7 @@ public function test_loading_template_part_with_hooked_blocks() {
 
 		$this->assertStringContainsString(
 			'<!-- wp:tests/hooked-before /-->'
-			. '<!-- wp:navigation {"layout":{"type":"flex","setCascadingProperties":true,"justifyContent":"right"}} /-->',
+			. '<!-- wp:navigation {"layout":{"type":"flex","setCascadingProperties":true,"justifyContent":"right"},"metadata":{"ignoredHookedBlocks":["tests/hooked-before"]}} /-->',
 			$template->content
 		);
 		$this->assertStringNotContainsString(
@@ -215,7 +215,7 @@ public function test_loading_pattern_with_hooked_blocks() {
 			$pattern['content']
 		);
 		$this->assertStringContainsString(
-			'<!-- wp:comments -->'
+			'<!-- wp:comments {"metadata":{"ignoredHookedBlocks":["tests/hooked-first-child"]}} -->'
 			. '<div class="wp-block-comments">'
 			. '<!-- wp:tests/hooked-first-child /-->',
 			str_replace( array( "\n", "\t" ), '', $pattern['content'] )
diff --git a/tests/phpunit/tests/blocks/wpBlockPatternsRegistry.php b/tests/phpunit/tests/blocks/wpBlockPatternsRegistry.php
index 01050a2c5f2ad..1cc0f472bcdab 100644
--- a/tests/phpunit/tests/blocks/wpBlockPatternsRegistry.php
+++ b/tests/phpunit/tests/blocks/wpBlockPatternsRegistry.php
@@ -381,14 +381,12 @@ public function test_get_all_registered_includes_hooked_blocks() {
 		$pattern_three['name']     = 'test/three';
 		$pattern_three['content'] .= '<!-- wp:tests/my-block /-->';
 
-		$expected = array(
-			$pattern_one,
-			$pattern_two,
-			$pattern_three,
-		);
-
 		$registered = $this->registry->get_all_registered();
-		$this->assertSame( $expected, $registered );
+		$this->assertCount( 3, $registered );
+		$this->assertStringEndsWith( '<!-- wp:tests/my-block /-->', $registered[1]['content'] );
+		$this->assertStringContainsString( '"metadata":{"ignoredHookedBlocks":["tests/my-block"]}', $registered[1]['content'] );
+		$this->assertStringEndsWith( '<!-- wp:tests/my-block /-->', $registered[2]['content'] );
+		$this->assertStringContainsString( '"metadata":{"ignoredHookedBlocks":["tests/my-block"]}', $registered[2]['content'] );
 	}
 
 	/**
@@ -444,11 +442,9 @@ public function test_get_registered_includes_hooked_blocks() {
 		);
 		$this->registry->register( 'test/two', $pattern_two );
 
-		$pattern_one['name']    = 'test/one';
-		$pattern_one['content'] = '<!-- wp:tests/my-block /-->' . $pattern_one['content'];
-
 		$pattern = $this->registry->get_registered( 'test/one' );
-		$this->assertSame( $pattern_one, $pattern );
+		$this->assertStringStartsWith( '<!-- wp:tests/my-block /-->', $pattern['content'] );
+		$this->assertStringContainsString( '"metadata":{"ignoredHookedBlocks":["tests/my-block"]}', $pattern['content'] );
 	}
 
 	/**