diff --git a/eng/pipelines/common/xplat-setup.yml b/eng/pipelines/common/xplat-setup.yml
index f12f7814b471b8..85c27e64f20388 100644
--- a/eng/pipelines/common/xplat-setup.yml
+++ b/eng/pipelines/common/xplat-setup.yml
@@ -47,6 +47,12 @@ jobs:
 
       - name: _BuildConfig
         value: $(buildConfigUpper)
+      
+      - name: _runSmokeTestsOnlyArg
+        ${{ if ne(parameters.variables['isFullMatrix'], true) }}:
+          value: /p:RunSmokeTestsOnly=true
+        ${{ if eq(parameters.variables['isFullMatrix'], true) }}:
+          value: ''
 
       - ${{ if or(eq(parameters.osGroup, 'windows'), eq(parameters.hostedOs, 'windows')) }}:
         - name: archiveExtension
diff --git a/eng/pipelines/runtime-staging.yml b/eng/pipelines/runtime-staging.yml
index 5235da8bd0b7c1..b9c723e0ebf7b7 100644
--- a/eng/pipelines/runtime-staging.yml
+++ b/eng/pipelines/runtime-staging.yml
@@ -212,7 +212,7 @@ jobs:
     jobParameters:
       testGroup: innerloop
       nameSuffix: AllSubsets_Mono
-      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true
+      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true $(_runSmokeTestsOnlyArg)
       timeoutInMinutes: 180
       condition: >-
         or(
@@ -249,7 +249,7 @@ jobs:
     jobParameters:
       testGroup: innerloop
       nameSuffix: AllSubsets_Mono
-      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true
+      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true $(_runSmokeTestsOnlyArg)
       timeoutInMinutes: 180
       condition: >-
         or(
@@ -257,8 +257,7 @@ jobs:
           eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
           eq(dependencies.evaluate_paths.outputs['SetPathVars_installer.containsChange'], true),
           eq(variables['isFullMatrix'], true))
-
-      # don't run tests on PRs until we can get significantly more devices
+      # Device tests are rolling build only
       ${{ if eq(variables['isFullMatrix'], true) }}:
         # extra steps, run tests
         extraStepsTemplate: /eng/pipelines/libraries/helix.yml
@@ -320,7 +319,7 @@ jobs:
     buildConfig: Release
     runtimeFlavor: mono
     platforms:
-    - Android_x64
+      - Android_x64
     variables:
       - ${{ if and(eq(variables['System.TeamProject'], 'public'), eq(variables['Build.Reason'], 'PullRequest')) }}:
         - name: _HelixSource
@@ -343,11 +342,13 @@ jobs:
           eq(dependencies.evaluate_paths.outputs['SetPathVars_runtimetests.containsChange'], true),
           eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
           eq(variables['isFullMatrix'], true))
-      # extra steps, run tests
-      extraStepsTemplate: /eng/pipelines/common/templates/runtimes/android-runtime-and-send-to-helix.yml
-      extraStepsParameters:
-        creator: dotnet-bot
-        testRunNamePrefixSuffix: Mono_$(_BuildConfig)
+      # NOTE: Per PR test execution is not recommended for runtime tests 
+      ${{ if eq(variables['isFullMatrix'], true) }}:
+        # extra steps, run tests
+        extraStepsTemplate: /eng/pipelines/common/templates/runtimes/android-runtime-and-send-to-helix.yml
+        extraStepsParameters:
+          creator: dotnet-bot
+          testRunNamePrefixSuffix: Mono_$(_BuildConfig)
 
 #
 # Build the whole product using Mono and run runtime tests with the JIT.
@@ -359,7 +360,7 @@ jobs:
     buildConfig: Release
     runtimeFlavor: mono
     platforms:
-    - iOSSimulator_x64
+      - iOSSimulator_x64
     variables:
       - ${{ if and(eq(variables['System.TeamProject'], 'public'), eq(variables['Build.Reason'], 'PullRequest')) }}:
         - name: _HelixSource
@@ -398,7 +399,7 @@ jobs:
     buildConfig: Release
     runtimeFlavor: mono
     platforms:
-    - Android_arm64
+      - Android_arm64
     variables:
       - ${{ if and(eq(variables['System.TeamProject'], 'public'), eq(variables['Build.Reason'], 'PullRequest')) }}:
         - name: _HelixSource
@@ -457,20 +458,21 @@ jobs:
           eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
           eq(dependencies.evaluate_paths.outputs['SetPathVars_installer.containsChange'], true),
           eq(variables['isFullMatrix'], true))
-      # extra steps, run tests
-      extraStepsTemplate: /eng/pipelines/libraries/helix.yml
-      extraStepsParameters:
-        creator: dotnet-bot
-        testRunNamePrefixSuffix: Mono_$(_BuildConfig)
-        extraHelixArguments: /p:BrowserHost=windows
-        scenarios:
-        - normal
-        - wasmtestonbrowser
-        condition: >-
-          or(
-          eq(variables['librariesContainsChange'], true),
-          eq(variables['monoContainsChange'], true),
-          eq(variables['isFullMatrix'], true))
+      ${{ if eq(variables['isFullMatrix'], true) }}:
+        # extra steps, run tests
+        extraStepsTemplate: /eng/pipelines/libraries/helix.yml
+        extraStepsParameters:
+          creator: dotnet-bot
+          testRunNamePrefixSuffix: Mono_$(_BuildConfig)
+          extraHelixArguments: /p:BrowserHost=windows
+          scenarios:
+          - normal
+          - wasmtestonbrowser
+          condition: >-
+            or(
+            eq(variables['librariesContainsChange'], true),
+            eq(variables['monoContainsChange'], true),
+            eq(variables['isFullMatrix'], true))
 
 #
 # CoreCLR Build for running Apple Silicon libraries-innerloop
diff --git a/eng/pipelines/runtime.yml b/eng/pipelines/runtime.yml
index 77b1cfbd9ba7e2..fefc64785cb7b2 100644
--- a/eng/pipelines/runtime.yml
+++ b/eng/pipelines/runtime.yml
@@ -292,7 +292,7 @@ jobs:
     jobParameters:
       testGroup: innerloop
       nameSuffix: AllSubsets_Mono
-      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true
+      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true $(_runSmokeTestsOnlyArg)
       timeoutInMinutes: 180
       condition: >-
         or(
@@ -305,6 +305,7 @@ jobs:
       extraStepsParameters:
         creator: dotnet-bot
         testRunNamePrefixSuffix: Mono_$(_BuildConfig)
+        extraHelixArguments: $(_runSmokeTestsOnlyArg)
         scenarios:
         - normal
         - wasmtestonbrowser
@@ -324,7 +325,9 @@ jobs:
     buildConfig: Release
     runtimeFlavor: mono
     platforms:
-    - Browser_wasm
+    # BuildWasmApps should only happen on the rolling build. No need to duplicate the build on PR's
+    - ${{ if eq(variables['isFullMatrix'], true) }}:
+      - Browser_wasm
     variables:
       # map dependencies variables to local variables
       - name: monoContainsChange
@@ -374,7 +377,7 @@ jobs:
     jobParameters:
       testGroup: innerloop
       nameSuffix: AllSubsets_Mono_EAT
-      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true /p:EnableAggressiveTrimming=true /p:BuildAOTTestsOnHelix=true /p:RunAOTCompilation=false
+      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true $(_runSmokeTestsOnlyArg) /p:EnableAggressiveTrimming=true /p:BuildAOTTestsOnHelix=true /p:RunAOTCompilation=false
       timeoutInMinutes: 180
       condition: >-
         or(
@@ -387,7 +390,7 @@ jobs:
       extraStepsParameters:
         creator: dotnet-bot
         testRunNamePrefixSuffix: Mono_$(_BuildConfig)
-        extraHelixArguments: /p:NeedsToBuildWasmAppsOnHelix=true
+        extraHelixArguments: /p:NeedsToBuildWasmAppsOnHelix=true $(_runSmokeTestsOnlyArg)
         scenarios:
         - normal
         condition: >-
@@ -416,7 +419,7 @@ jobs:
     jobParameters:
       testGroup: innerloop
       nameSuffix: AllSubsets_Mono_AOT
-      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true /p:EnableAggressiveTrimming=true /p:BuildAOTTestsOnHelix=true /p:RunAOTCompilation=true
+      buildArgs: -s mono+libs+host+packs+libs.tests -c $(_BuildConfig) /p:ArchiveTests=true $(_runSmokeTestsOnlyArg) /p:EnableAggressiveTrimming=true /p:BuildAOTTestsOnHelix=true /p:RunAOTCompilation=true
       timeoutInMinutes: 180
       condition: >-
         or(
@@ -429,7 +432,7 @@ jobs:
       extraStepsParameters:
         creator: dotnet-bot
         testRunNamePrefixSuffix: Mono_$(_BuildConfig)
-        extraHelixArguments: /p:NeedsToBuildWasmAppsOnHelix=true
+        extraHelixArguments: /p:NeedsToBuildWasmAppsOnHelix=true $(_runSmokeTestsOnlyArg)
         scenarios:
         - normal
         condition: >-
@@ -488,10 +491,8 @@ jobs:
       buildArgs: -s mono+libs -c $(_BuildConfig)
       timeoutInMinutes: 180
       condition: >-
-        or(
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_runtimetests.containsChange'], true),
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
-          eq(variables['isFullMatrix'], true))
+        eq(variables['isFullMatrix'], true)
+      # NOTE: Per PR test execution is not recommended for mobile runtime tests
       # extra steps, run tests
       extraStepsTemplate: /eng/pipelines/common/templates/runtimes/wasm-runtime-and-send-to-helix.yml
       extraStepsParameters:
@@ -526,10 +527,8 @@ jobs:
       buildArgs: -s mono+libs -c $(_BuildConfig)
       timeoutInMinutes: 240
       condition: >-
-        or(
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_runtimetests.containsChange'], true),
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
-          eq(variables['isFullMatrix'], true))
+        eq(variables['isFullMatrix'], true)
+      # NOTE: Per PR test execution is not recommended for mobile runtime tests
       # extra steps, run tests
       extraStepsTemplate: /eng/pipelines/common/templates/runtimes/android-runtime-and-send-to-helix.yml
       extraStepsParameters:
@@ -1042,10 +1041,7 @@ jobs:
       liveRuntimeBuildConfig: release
       runtimeVariant: minijit
       condition: >-
-        or(
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_runtimetests.containsChange'], true),
-          eq(variables['isFullMatrix'], true))
+        eq(variables['isFullMatrix'], true)
 
 #
 # Mono CoreCLR runtime Test executions using live libraries in interpreter mode
@@ -1066,10 +1062,7 @@ jobs:
       liveRuntimeBuildConfig: release
       runtimeVariant: monointerpreter
       condition: >-
-        or(
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_runtimetests.containsChange'], true),
-          eq(variables['isFullMatrix'], true))
+        eq(variables['isFullMatrix'], true)
 #
 # Mono CoreCLR runtime Test executions using live libraries and LLVM AOT
 # Only when Mono is changed
@@ -1091,10 +1084,7 @@ jobs:
       liveRuntimeBuildConfig: release
       runtimeVariant: llvmaot
       condition: >-
-        or(
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_runtimetests.containsChange'], true),
-          eq(variables['isFullMatrix'], true))
+        eq(variables['isFullMatrix'], true)
 
 #
 # Mono CoreCLR runtime Test executions using live libraries and LLVM Full AOT
@@ -1117,10 +1107,7 @@ jobs:
       liveRuntimeBuildConfig: release
       runtimeVariant: llvmfullaot
       condition: >-
-        or(
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_mono.containsChange'], true),
-          eq(dependencies.evaluate_paths.outputs['SetPathVars_runtimetests.containsChange'], true),
-          eq(variables['isFullMatrix'], true))
+        eq(variables['isFullMatrix'], true)
 
 #
 # Libraries Release Test Execution against a release mono runtime.
@@ -1288,4 +1275,4 @@ jobs:
         or(
           eq(dependencies.evaluate_paths.outputs['SetPathVars_coreclr.containsChange'], true),
           eq(dependencies.evaluate_paths.outputs['SetPathVars_libraries.containsChange'], true),
-          eq(variables['isFullMatrix'], true))
+          eq(variables['isFullMatrix'], true))
\ No newline at end of file
diff --git a/src/libraries/sendtohelixhelp.proj b/src/libraries/sendtohelixhelp.proj
index 90baea4148aebc..5eda5fb86a2aee 100644
--- a/src/libraries/sendtohelixhelp.proj
+++ b/src/libraries/sendtohelixhelp.proj
@@ -392,7 +392,7 @@
       <HelixCorrelationPayload Include="$(MonoTargetsTasksDir)"                  Destination="build/MonoTargetsTasks" />
     </ItemGroup>
 
-    <ItemGroup Condition="'$(TargetOS)' == 'Browser' and '$(Scenario)' != 'BuildWasmApps'">
+    <ItemGroup Condition="'$(TargetOS)' == 'Browser' and '$(RunSmokeTestsOnly)' != 'true' and '$(Scenario)' != 'BuildWasmApps'">
       <HelixCorrelationPayload Include="$(TestEchoMiddleware)" Destination="xharness/TestEchoMiddleware" />
       <HelixCorrelationPayload Include="$(RemoteLoopMiddleware)" Destination="xharness/RemoteLoopMiddleware" />
     </ItemGroup>
diff --git a/src/libraries/tests.proj b/src/libraries/tests.proj
index 913a97376183d2..559309ed23fc0f 100644
--- a/src/libraries/tests.proj
+++ b/src/libraries/tests.proj
@@ -285,7 +285,11 @@
     <ProjectExclusions Remove="$(MSBuildThisFileDirectory)System.IO.IsolatedStorage\tests\System.IO.IsolatedStorage.Tests.csproj" />
   </ItemGroup>
 
-  <ItemGroup>
+  <ItemGroup Condition="'$(RunSmokeTestsOnly)' == 'true'">
+    <ProjectReference Include="$(MSBuildThisFileDirectory)System.Runtime\tests\System.Runtime.Tests.csproj" />
+  </ItemGroup>
+
+  <ItemGroup Condition="'$(RunSmokeTestsOnly)' != 'true'">
     <ProjectReference Include="$(MSBuildThisFileDirectory)*\tests\**\*.Tests.csproj"
                       Exclude="@(ProjectExclusions)"
                       Condition="'$(TestAssemblies)' == 'true'" />
@@ -344,7 +348,7 @@
                       BuildInParallel="false" />
   </ItemGroup>
 
-  <ItemGroup Condition="'$(ArchiveTests)' == 'true' and '$(TargetOS)' == 'Android'">
+  <ItemGroup Condition="'$(ArchiveTests)' == 'true' and '$(RunSmokeTestsOnly)' != 'true' and '$(TargetOS)' == 'Android'">
     <ProjectReference Include="$(MonoProjectRoot)sample\Android\AndroidSampleApp.csproj"
                       BuildInParallel="false" />
     <ProjectReference Include="$(RepoRoot)\src\tests\FunctionalTests\Android\**\*.Test.csproj"
@@ -353,7 +357,7 @@
   </ItemGroup>
 
   <!-- Don't build samples, and functional tests on EAT, AOT, and WBT lanes -->
-  <ItemGroup Condition="'$(ArchiveTests)' == 'true' and '$(TargetOS)' == 'Browser' and '$(BuildAOTTestsOnHelix)' != 'true' and '$(TestWasmBuildTests)' != 'true'">
+  <ItemGroup Condition="'$(ArchiveTests)' == 'true' and '$(RunSmokeTestsOnly)' != 'true' and '$(TargetOS)' == 'Browser' and '$(BuildAOTTestsOnHelix)' != 'true' and '$(TestWasmBuildTests)' != 'true'">
     <ProjectReference Include="$(MonoProjectRoot)sample\wasm\**\*.Sample.csproj"
                       Exclude="@(ProjectExclusions)"
                       BuildInParallel="true" />