diff --git a/src/libraries/Common/src/System/Collections/Generic/BitHelper.cs b/src/libraries/Common/src/System/Collections/Generic/BitHelper.cs
index 01f0c1cd6862f0..05f353bb72d510 100644
--- a/src/libraries/Common/src/System/Collections/Generic/BitHelper.cs
+++ b/src/libraries/Common/src/System/Collections/Generic/BitHelper.cs
@@ -1,6 +1,8 @@
 // Licensed to the .NET Foundation under one or more agreements.
 // The .NET Foundation licenses this file to you under the MIT license.
 
+using System.Diagnostics;
+
 namespace System.Collections.Generic
 {
     internal ref struct BitHelper
@@ -19,19 +21,29 @@ internal BitHelper(Span<int> span, bool clear)
 
         internal void MarkBit(int bitPosition)
         {
-            int bitArrayIndex = bitPosition / IntSize;
-            if ((uint)bitArrayIndex < (uint)_span.Length)
+            Debug.Assert(bitPosition >= 0);
+
+            uint bitArrayIndex = (uint)bitPosition / IntSize;
+
+            // Workaround for https://github.com/dotnet/runtime/issues/72004
+            Span<int> span = _span;
+            if (bitArrayIndex < (uint)span.Length)
             {
-                _span[bitArrayIndex] |= (1 << (bitPosition % IntSize));
+                span[(int)bitArrayIndex] |= (1 << (int)((uint)bitPosition % IntSize));
             }
         }
 
         internal bool IsMarked(int bitPosition)
         {
-            int bitArrayIndex = bitPosition / IntSize;
+            Debug.Assert(bitPosition >= 0);
+
+            uint bitArrayIndex = (uint)bitPosition / IntSize;
+
+            // Workaround for https://github.com/dotnet/runtime/issues/72004
+            Span<int> span = _span;
             return
-                (uint)bitArrayIndex < (uint)_span.Length &&
-                (_span[bitArrayIndex] & (1 << (bitPosition % IntSize))) != 0;
+                bitArrayIndex < (uint)span.Length &&
+                (span[(int)bitArrayIndex] & (1 << ((int)((uint)bitPosition % IntSize)))) != 0;
         }
 
         /// <summary>How many ints must be allocated to represent n bits. Returns (n+31)/32, but avoids overflow.</summary>
diff --git a/src/libraries/System.Private.CoreLib/src/System/Boolean.cs b/src/libraries/System.Private.CoreLib/src/System/Boolean.cs
index 722b1b6cfa9881..885e1db1b74bb9 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Boolean.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Boolean.cs
@@ -99,7 +99,7 @@ public bool TryFormat(Span<char> destination, out int charsWritten)
         {
             if (m_value)
             {
-                if ((uint)destination.Length > 3) // uint cast, per https://github.com/dotnet/runtime/issues/10596
+                if (destination.Length > 3)
                 {
                     ulong true_val = BitConverter.IsLittleEndian ? 0x65007500720054ul : 0x54007200750065ul; // "True"
                     MemoryMarshal.Write<ulong>(MemoryMarshal.AsBytes(destination), ref true_val);
@@ -109,7 +109,7 @@ public bool TryFormat(Span<char> destination, out int charsWritten)
             }
             else
             {
-                if ((uint)destination.Length > 4)
+                if (destination.Length > 4)
                 {
                     ulong fals_val = BitConverter.IsLittleEndian ? 0x73006C00610046ul : 0x460061006C0073ul; // "Fals"
                     MemoryMarshal.Write<ulong>(MemoryMarshal.AsBytes(destination), ref fals_val);
diff --git a/src/libraries/System.Private.CoreLib/src/System/Buffers/StandardFormat.cs b/src/libraries/System.Private.CoreLib/src/System/Buffers/StandardFormat.cs
index 1ad5884afd33c1..784b08c5ec5559 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Buffers/StandardFormat.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Buffers/StandardFormat.cs
@@ -164,8 +164,7 @@ internal int Format(Span<char> destination)
             int count = 0;
             char symbol = Symbol;
 
-            if (symbol != default &&
-                (uint)destination.Length == FormatStringLength) // to eliminate bounds checks
+            if (symbol != default && destination.Length == FormatStringLength)
             {
                 destination[0] = symbol;
                 count = 1;
diff --git a/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Boolean.cs b/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Boolean.cs
index b23cc3a28c8794..220a49308ff4ec 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Boolean.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Boolean.cs
@@ -65,7 +65,7 @@ public static bool TryFormat(bool value, Span<byte> destination, out int bytesWr
                 {
                     // This check can't be performed earlier because we need to throw if an invalid symbol is
                     // provided, even if the buffer is too small.
-                    if ((uint)4 >= (uint)destination.Length)
+                    if (destination.Length <= 4)
                     {
                         goto BufferTooSmall;
                     }
@@ -75,7 +75,7 @@ public static bool TryFormat(bool value, Span<byte> destination, out int bytesWr
                 }
                 else if (symbol == 'l')
                 {
-                    if ((uint)4 >= (uint)destination.Length)
+                    if (destination.Length <= 4)
                     {
                         goto BufferTooSmall;
                     }
diff --git a/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Date.L.cs b/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Date.L.cs
index 0f20a2ab55e7be..6d4dc6143dc5c1 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Date.L.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Date.L.cs
@@ -13,9 +13,7 @@ public static partial class Utf8Formatter
         //
         private static bool TryFormatDateTimeL(DateTime value, Span<byte> destination, out int bytesWritten)
         {
-            // Writing the check in this fashion elides all bounds checks on 'buffer'
-            // for the remainder of the method.
-            if ((uint)28 >= (uint)destination.Length)
+            if (destination.Length <= 28)
             {
                 bytesWritten = 0;
                 return false;
diff --git a/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Date.R.cs b/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Date.R.cs
index 9c9738dbb135b3..d80b27cd26c8b0 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Date.R.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Buffers/Text/Utf8Formatter/Utf8Formatter.Date.R.cs
@@ -13,9 +13,7 @@ public static partial class Utf8Formatter
         //
         private static bool TryFormatDateTimeR(DateTime value, Span<byte> destination, out int bytesWritten)
         {
-            // Writing the check in this fashion elides all bounds checks on 'buffer'
-            // for the remainder of the method.
-            if ((uint)28 >= (uint)destination.Length)
+            if (destination.Length <= 28)
             {
                 bytesWritten = 0;
                 return false;
diff --git a/src/libraries/System.Private.CoreLib/src/System/Char.cs b/src/libraries/System.Private.CoreLib/src/System/Char.cs
index 345139f5d32bcc..c7fbf1d8d78351 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Char.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Char.cs
@@ -591,7 +591,7 @@ public static bool IsControl(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -606,7 +606,7 @@ public static bool IsDigit(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -626,7 +626,7 @@ public static bool IsLetter(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -647,7 +647,7 @@ public static bool IsLetterOrDigit(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -667,8 +667,7 @@ public static bool IsLower(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -710,7 +709,7 @@ public static bool IsNumber(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -743,7 +742,7 @@ public static bool IsPunctuation(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -788,7 +787,7 @@ public static bool IsSeparator(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -813,7 +812,7 @@ public static bool IsSurrogate(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -845,7 +844,7 @@ public static bool IsSymbol(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -865,7 +864,7 @@ public static bool IsUpper(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -885,7 +884,7 @@ public static bool IsWhiteSpace(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -911,7 +910,7 @@ public static UnicodeCategory GetUnicodeCategory(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -935,7 +934,7 @@ public static double GetNumericValue(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -957,7 +956,7 @@ public static bool IsHighSurrogate(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -979,7 +978,7 @@ public static bool IsLowSurrogate(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
@@ -996,7 +995,7 @@ public static bool IsSurrogatePair(string s, int index)
             {
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.s);
             }
-            if (((uint)index) >= ((uint)s.Length))
+            if ((uint)index >= (uint)s.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRangeException(ExceptionArgument.index);
             }
diff --git a/src/libraries/System.Private.CoreLib/src/System/Collections/Generic/ValueListBuilder.cs b/src/libraries/System.Private.CoreLib/src/System/Collections/Generic/ValueListBuilder.cs
index 72b25bc2d9dd33..a30e63947f1837 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Collections/Generic/ValueListBuilder.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Collections/Generic/ValueListBuilder.cs
@@ -44,9 +44,12 @@ public ref T this[int index]
         public void Append(T item)
         {
             int pos = _pos;
-            if ((uint)pos < (uint)_span.Length)
+
+            // Workaround for https://github.com/dotnet/runtime/issues/72004
+            Span<T> span = _span;
+            if ((uint)pos < (uint)span.Length)
             {
-                _span[pos] = item;
+                span[pos] = item;
                 _pos = pos + 1;
             }
             else
diff --git a/src/libraries/System.Private.CoreLib/src/System/Decimal.cs b/src/libraries/System.Private.CoreLib/src/System/Decimal.cs
index 13abf7bb8f83c5..4f2f9693d1df09 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Decimal.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Decimal.cs
@@ -602,7 +602,7 @@ public static int[] GetBits(decimal d)
         /// <exception cref="ArgumentException">The destination span was not long enough to store the binary representation.</exception>
         public static int GetBits(decimal d, Span<int> destination)
         {
-            if ((uint)destination.Length <= 3)
+            if (destination.Length <= 3)
             {
                 ThrowHelper.ThrowArgumentException_DestinationTooShort();
             }
@@ -623,7 +623,7 @@ public static int GetBits(decimal d, Span<int> destination)
         /// <returns>true if the decimal's binary representation was written to the destination; false if the destination wasn't long enough.</returns>
         public static bool TryGetBits(decimal d, Span<int> destination, out int valuesWritten)
         {
-            if ((uint)destination.Length <= 3)
+            if (destination.Length <= 3)
             {
                 valuesWritten = 0;
                 return false;
diff --git a/src/libraries/System.Private.CoreLib/src/System/Globalization/DateTimeParse.cs b/src/libraries/System.Private.CoreLib/src/System/Globalization/DateTimeParse.cs
index a67fa5cca0be58..8ca810d210332c 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Globalization/DateTimeParse.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Globalization/DateTimeParse.cs
@@ -4668,7 +4668,7 @@ private static bool ParseFormatR(ReadOnlySpan<char> source, ref ParsingInfo pars
             // Tue, 03 Jan 2017 08:08:05 GMT
 
             // The format is exactly 29 characters.
-            if ((uint)source.Length != 29)
+            if (source.Length != 29)
             {
                 result.SetBadDateTimeFailure();
                 return false;
@@ -4865,7 +4865,7 @@ private static bool ParseFormatO(ReadOnlySpan<char> source, ref DateTimeResult r
             // 2017-06-12T05:30:45.7680000-7:00   (special-case of one-digit offset hour)
             // 2017-06-12T05:30:45.7680000-07:00
 
-            if ((uint)source.Length < 27 ||
+            if (source.Length < 27 ||
                 source[4] != '-' ||
                 source[7] != '-' ||
                 source[10] != 'T' ||
@@ -4986,7 +4986,7 @@ private static bool ParseFormatO(ReadOnlySpan<char> source, ref DateTimeResult r
                 return false;
             }
 
-            if ((uint)source.Length > 27)
+            if (source.Length > 27)
             {
                 char offsetChar = source[27];
                 switch (offsetChar)
@@ -5004,7 +5004,7 @@ private static bool ParseFormatO(ReadOnlySpan<char> source, ref DateTimeResult r
                     case '-':
                         int offsetHours, colonIndex;
 
-                        if ((uint)source.Length == 33)
+                        if (source.Length == 33)
                         {
                             uint oh1 = (uint)(source[28] - '0'), oh2 = (uint)(source[29] - '0');
 
@@ -5017,7 +5017,7 @@ private static bool ParseFormatO(ReadOnlySpan<char> source, ref DateTimeResult r
                             offsetHours = (int)(oh1 * 10 + oh2);
                             colonIndex = 30;
                         }
-                        else if ((uint)source.Length == 32) // special-case allowed for compat: only one offset hour digit
+                        else if (source.Length == 32) // special-case allowed for compat: only one offset hour digit
                         {
                             offsetHours = source[28] - '0';
 
diff --git a/src/libraries/System.Private.CoreLib/src/System/Globalization/TimeSpanParse.cs b/src/libraries/System.Private.CoreLib/src/System/Globalization/TimeSpanParse.cs
index 362d80323aced8..729302efe85b2f 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Globalization/TimeSpanParse.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Globalization/TimeSpanParse.cs
@@ -169,15 +169,17 @@ internal TimeSpanToken GetNextToken()
             {
                 // Get the position of the next character to be processed.  If there is no
                 // next character, we're at the end.
-                int pos = _pos;
+                int startPos = _pos;
+                int pos = startPos;
+                ReadOnlySpan<char> value = _value;
                 Debug.Assert(pos > -1);
-                if (pos >= _value.Length)
+                if ((uint)pos >= (uint)value.Length)
                 {
                     return new TimeSpanToken(TTT.End);
                 }
 
                 // Now retrieve that character. If it's a digit, we're processing a number.
-                int num = _value[pos] - '0';
+                int num = value[pos] - '0';
                 if ((uint)num <= 9)
                 {
                     int zeroes = 0;
@@ -188,8 +190,9 @@ internal TimeSpanToken GetNextToken()
                         while (true)
                         {
                             int digit;
-                            if (++_pos >= _value.Length || (uint)(digit = _value[_pos] - '0') > 9)
+                            if ((uint)++pos >= (uint)value.Length || (uint)(digit = value[pos] - '0') > 9)
                             {
+                                _pos = pos;
                                 return new TimeSpanToken(TTT.Num, 0, zeroes, default);
                             }
 
@@ -202,12 +205,14 @@ internal TimeSpanToken GetNextToken()
                             num = digit;
                             break;
                         }
+
+                        _pos = pos;
                     }
 
                     // Continue to read as long as we're reading digits.
-                    while (++_pos < _value.Length)
+                    while ((uint)++pos < (uint)value.Length)
                     {
-                        int digit = _value[_pos] - '0';
+                        int digit = value[pos] - '0';
                         if ((uint)digit > 9)
                         {
                             break;
@@ -216,27 +221,26 @@ internal TimeSpanToken GetNextToken()
                         num = num * 10 + digit;
                         if ((num & 0xF0000000) != 0) // Max limit we can support 268435455 which is FFFFFFF
                         {
+                            _pos = pos;
                             return new TimeSpanToken(TTT.NumOverflow);
                         }
                     }
 
+                    _pos = pos;
                     return new TimeSpanToken(TTT.Num, num, zeroes, default);
                 }
 
                 // Otherwise, we're processing a separator, and we've already processed the first
                 // character of it.  Continue processing characters as long as they're not digits.
                 int length = 1;
-                while (true)
+                while ((uint)++pos < (uint)value.Length && !char.IsAsciiDigit(value[pos]))
                 {
-                    if (++_pos >= _value.Length || char.IsAsciiDigit(_value[_pos]))
-                    {
-                        break;
-                    }
                     length++;
                 }
+                _pos = pos;
 
                 // Return the separator.
-                return new TimeSpanToken(TTT.Sep, 0, 0, _value.Slice(pos, length));
+                return new TimeSpanToken(TTT.Sep, 0, 0, _value.Slice(startPos, length));
             }
 
             internal bool EOL => _pos >= (_value.Length - 1);
@@ -249,7 +253,7 @@ internal void BackOne()
             internal char NextChar()
             {
                 int pos = ++_pos;
-                return (uint)pos < (uint)_value.Length?
+                return (uint)pos < (uint)_value.Length ?
                     _value[pos] :
                     (char)0;
             }
diff --git a/src/libraries/System.Private.CoreLib/src/System/Guid.cs b/src/libraries/System.Private.CoreLib/src/System/Guid.cs
index 553385996fe25d..7c2b759aa880d6 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Guid.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Guid.cs
@@ -48,7 +48,7 @@ public Guid(byte[] b) :
         // Creates a new guid from a read-only span.
         public Guid(ReadOnlySpan<byte> b)
         {
-            if ((uint)b.Length != 16)
+            if (b.Length != 16)
             {
                 throw new ArgumentException(SR.Format(SR.Arg_GuidArrayCtor, "16"), nameof(b));
             }
@@ -378,7 +378,7 @@ private static bool TryParseExactB(ReadOnlySpan<char> guidString, ref GuidResult
         {
             // e.g. "{d85b1407-351d-4694-9392-03acc5870eb1}"
 
-            if ((uint)guidString.Length != 38 || guidString[0] != '{' || guidString[37] != '}')
+            if (guidString.Length != 38 || guidString[0] != '{' || guidString[37] != '}')
             {
                 result.SetFailure(overflow: false, nameof(SR.Format_GuidInvLen));
                 return false;
@@ -391,7 +391,7 @@ private static bool TryParseExactD(ReadOnlySpan<char> guidString, ref GuidResult
         {
             // e.g. "d85b1407-351d-4694-9392-03acc5870eb1"
 
-            if ((uint)guidString.Length != 36 || guidString[8] != '-' || guidString[13] != '-' || guidString[18] != '-' || guidString[23] != '-')
+            if (guidString.Length != 36 || guidString[8] != '-' || guidString[13] != '-' || guidString[18] != '-' || guidString[23] != '-')
             {
                 result.SetFailure(overflow: false, guidString.Length != 36 ? nameof(SR.Format_GuidInvLen) : nameof(SR.Format_GuidDashes));
                 return false;
@@ -477,7 +477,7 @@ private static bool TryParseExactN(ReadOnlySpan<char> guidString, ref GuidResult
         {
             // e.g. "d85b1407351d4694939203acc5870eb1"
 
-            if ((uint)guidString.Length != 32)
+            if (guidString.Length != 32)
             {
                 result.SetFailure(overflow: false, nameof(SR.Format_GuidInvLen));
                 return false;
@@ -520,7 +520,7 @@ private static bool TryParseExactP(ReadOnlySpan<char> guidString, ref GuidResult
         {
             // e.g. "(d85b1407-351d-4694-9392-03acc5870eb1)"
 
-            if ((uint)guidString.Length != 38 || guidString[0] != '(' || guidString[37] != ')')
+            if (guidString.Length != 38 || guidString[0] != '(' || guidString[37] != ')')
             {
                 result.SetFailure(overflow: false, nameof(SR.Format_GuidInvLen));
                 return false;
@@ -547,7 +547,7 @@ private static bool TryParseExactX(ReadOnlySpan<char> guidString, ref GuidResult
             guidString = EatAllWhitespace(guidString);
 
             // Check for leading '{'
-            if ((uint)guidString.Length == 0 || guidString[0] != '{')
+            if (guidString.Length == 0 || guidString[0] != '{')
             {
                 result.SetFailure(overflow: false, nameof(SR.Format_GuidBrace));
                 return false;
@@ -735,14 +735,14 @@ private static bool TryParseHex(ReadOnlySpan<char> guidString, out uint result)
 
         private static bool TryParseHex(ReadOnlySpan<char> guidString, out uint result, ref bool overflow)
         {
-            if ((uint)guidString.Length > 0)
+            if (guidString.Length > 0)
             {
                 if (guidString[0] == '+')
                 {
                     guidString = guidString.Slice(1);
                 }
 
-                if ((uint)guidString.Length > 1 && guidString[0] == '0' && (guidString[1] | 0x20) == 'x')
+                if (guidString.Length > 1 && guidString[0] == '0' && (guidString[1] | 0x20) == 'x')
                 {
                     guidString = guidString.Slice(2);
                 }
diff --git a/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/DefaultInterpolatedStringHandler.cs b/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/DefaultInterpolatedStringHandler.cs
index 8e441b6885616f..3b46f1909ebde9 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/DefaultInterpolatedStringHandler.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Runtime/CompilerServices/DefaultInterpolatedStringHandler.cs
@@ -154,8 +154,8 @@ public void AppendLiteral(string value)
 
             if (value.Length == 1)
             {
-                Span<char> chars = _chars;
                 int pos = _pos;
+                Span<char> chars = _chars;
                 if ((uint)pos < (uint)chars.Length)
                 {
                     chars[pos] = value[0];
@@ -170,12 +170,11 @@ public void AppendLiteral(string value)
 
             if (value.Length == 2)
             {
-                Span<char> chars = _chars;
                 int pos = _pos;
-                if ((uint)pos < chars.Length - 1)
+                if ((uint)pos < _chars.Length - 1)
                 {
                     Unsafe.WriteUnaligned(
-                        ref Unsafe.As<char, byte>(ref Unsafe.Add(ref MemoryMarshal.GetReference(chars), pos)),
+                        ref Unsafe.As<char, byte>(ref Unsafe.Add(ref MemoryMarshal.GetReference(_chars), pos)),
                         Unsafe.ReadUnaligned<int>(ref Unsafe.As<char, byte>(ref value.GetRawStringData())));
                     _pos = pos + 2;
                 }
diff --git a/src/libraries/System.Private.CoreLib/src/System/Text/Rune.cs b/src/libraries/System.Private.CoreLib/src/System/Text/Rune.cs
index 1cd73a526e5e48..182863b8dcd65e 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Text/Rune.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Text/Rune.cs
@@ -842,7 +842,7 @@ private static int ReadRuneFromString(string input, int index)
                 ThrowHelper.ThrowArgumentNullException(ExceptionArgument.input);
             }
 
-            if ((uint)index >= (uint)input!.Length)
+            if ((uint)index >= (uint)input.Length)
             {
                 ThrowHelper.ThrowArgumentOutOfRange_IndexMustBeLessException();
             }
@@ -1019,7 +1019,7 @@ private static bool TryEncodeToUtf16(Rune value, Span<char> destination, out int
                     charsWritten = 1;
                     return true;
                 }
-                else if (1 < (uint)destination.Length)
+                else if (destination.Length > 1)
                 {
                     UnicodeUtility.GetUtf16SurrogatesFromSupplementaryPlaneScalar((uint)value._value, out destination[0], out destination[1]);
                     charsWritten = 2;
@@ -1066,7 +1066,7 @@ private static bool TryEncodeToUtf8(Rune value, Span<byte> destination, out int
                     return true;
                 }
 
-                if (1 < (uint)destination.Length)
+                if (destination.Length > 1)
                 {
                     if (value.Value <= 0x7FFu)
                     {
@@ -1077,7 +1077,7 @@ private static bool TryEncodeToUtf8(Rune value, Span<byte> destination, out int
                         return true;
                     }
 
-                    if (2 < (uint)destination.Length)
+                    if (destination.Length > 2)
                     {
                         if (value.Value <= 0xFFFFu)
                         {
@@ -1089,7 +1089,7 @@ private static bool TryEncodeToUtf8(Rune value, Span<byte> destination, out int
                             return true;
                         }
 
-                        if (3 < (uint)destination.Length)
+                        if (destination.Length > 3)
                         {
                             // Scalar 000uuuuu zzzzyyyy yyxxxxxx -> bytes [ 11110uuu 10uuzzzz 10yyyyyy 10xxxxxx ]
                             destination[0] = (byte)((value._value + (0b11110 << 21)) >> 18);
diff --git a/src/libraries/System.Private.CoreLib/src/System/Text/StringBuilder.cs b/src/libraries/System.Private.CoreLib/src/System/Text/StringBuilder.cs
index 2ef8aca4a795dc..9a4916dba7d896 100644
--- a/src/libraries/System.Private.CoreLib/src/System/Text/StringBuilder.cs
+++ b/src/libraries/System.Private.CoreLib/src/System/Text/StringBuilder.cs
@@ -1057,10 +1057,10 @@ public StringBuilder Append(char value)
             int nextCharIndex = m_ChunkLength;
             char[] chars = m_ChunkChars;
 
-            if ((uint)chars.Length > (uint)nextCharIndex)
+            if ((uint)nextCharIndex < (uint)chars.Length)
             {
                 chars[nextCharIndex] = value;
-                m_ChunkLength++;
+                m_ChunkLength = nextCharIndex + 1;
             }
             else
             {