diff --git a/src/coreclr/jit/morph.cpp b/src/coreclr/jit/morph.cpp
index e36feb309892e6..fb5932bb6e6aac 100644
--- a/src/coreclr/jit/morph.cpp
+++ b/src/coreclr/jit/morph.cpp
@@ -3270,6 +3270,18 @@ GenTreeCall* Compiler::fgMorphArgs(GenTreeCall* call)
                         makeOutArgCopy = true;
                     }
 
+                    // If the arg may go into registers (both fully or split)
+                    // then we cannot handle passing it from an arbitrary
+                    // source if it would require passing a 3 byte chunk.
+                    // Placing 3 bytes into a register requires multiple loads/shifts/or.
+                    // In theory we could more easily support it for split args
+                    // as those load registers fully always, but currently we
+                    // do not.
+                    if ((arg.AbiInfo.NumRegs > 0) && ((passingSize % REGSIZE_BYTES) == 3))
+                    {
+                        makeOutArgCopy = true;
+                    }
+
                     if (structSize < TARGET_POINTER_SIZE)
                     {
                         makeOutArgCopy = true;
@@ -3854,7 +3866,7 @@ GenTree* Compiler::fgMorphMultiregStructArg(CallArg* arg)
                         break;
 #endif // (TARGET_ARM64) || (UNIX_AMD64_ABI) || (TARGET_LOONGARCH64)
                     default:
-                        noway_assert(!"NYI: odd sized struct in fgMorphMultiregStructArg");
+                        noway_assert(!"Cannot load odd sized last element from arbitrary source");
                         break;
                 }
             }
diff --git a/src/tests/JIT/Directed/StructABI/SevenByteStruct.cs b/src/tests/JIT/Directed/StructABI/SevenByteStruct.cs
new file mode 100644
index 00000000000000..b8924b99bc417f
--- /dev/null
+++ b/src/tests/JIT/Directed/StructABI/SevenByteStruct.cs
@@ -0,0 +1,35 @@
+// Licensed to the .NET Foundation under one or more agreements.
+// The .NET Foundation licenses this file to you under the MIT license.
+
+using System.Runtime.CompilerServices;
+
+// On ARM32 the following has S0 passed in two registers, which requires passing 3 bytes in the last register.
+// We cannot do that in a single load from an arbitrary source and must copy it to a local first.
+
+public struct S0
+{
+    public byte F0;
+    public byte F1;
+    public byte F2;
+    public byte F3;
+    public byte F4;
+    public byte F5;
+    public byte F6;
+}
+
+public class SevenByteStruct
+{
+    public static S0 s_4 = new S0 { F0 = 1, F1 = 2, F2 = 3, F3 = 4, F4 = 5, F5 = 6, F6 = 7 };
+    public static int Main()
+    {
+        ref S0 vr0 = ref s_4;
+        int sum = M35(vr0);
+        return sum == 28 ? 100 : -1;
+    }
+
+    [MethodImpl(MethodImplOptions.NoInlining)]
+    public static int M35(S0 arg0)
+    {
+        return arg0.F0 + arg0.F1 + arg0.F2 + arg0.F3 + arg0.F4 + arg0.F5 + arg0.F6;
+    }
+}
diff --git a/src/tests/JIT/Directed/StructABI/SevenByteStruct.csproj b/src/tests/JIT/Directed/StructABI/SevenByteStruct.csproj
new file mode 100644
index 00000000000000..9d281a449d0710
--- /dev/null
+++ b/src/tests/JIT/Directed/StructABI/SevenByteStruct.csproj
@@ -0,0 +1,12 @@
+<Project Sdk="Microsoft.NET.Sdk">
+  <PropertyGroup>
+    <OutputType>Exe</OutputType>
+  </PropertyGroup>
+  <PropertyGroup>
+    <DebugType>PdbOnly</DebugType>
+    <Optimize>True</Optimize>
+  </PropertyGroup>
+  <ItemGroup>
+    <Compile Include="SevenByteStruct.cs" />
+  </ItemGroup>
+</Project>
diff --git a/src/tests/issues.targets b/src/tests/issues.targets
index 47fb27b300a780..0637d41ba60411 100644
--- a/src/tests/issues.targets
+++ b/src/tests/issues.targets
@@ -543,12 +543,6 @@
         <ExcludeList Include="$(XunitTestBinBase)/JIT/Stress/ABI/pinvokes_do/**">
             <Issue>https://github.com/dotnet/runtime/issues/66745</Issue>
         </ExcludeList>
-        <ExcludeList Include="$(XunitTestBinBase)/JIT/Stress/ABI/tailcalls_d/**">
-            <Issue>https://github.com/dotnet/runtime/issues/70042</Issue>
-        </ExcludeList>
-        <ExcludeList Include="$(XunitTestBinBase)/JIT/Stress/ABI/tailcalls_do/**">
-            <Issue>https://github.com/dotnet/runtime/issues/70042</Issue>
-        </ExcludeList>
     </ItemGroup>
 
     <!-- Windows arm64 specific excludes -->
@@ -678,18 +672,6 @@
         <ExcludeList Include="$(XunitTestBinBase)/JIT/Regression/JitBlue/Runtime_56953/Runtime_56953/*">
             <Issue>https://github.com/dotnet/runtime/issues/57856</Issue>
         </ExcludeList>
-        <ExcludeList Include = "$(XunitTestBinBase)/JIT/Stress/ABI/tailcalls_d/**">
-            <Issue>https://github.com/dotnet/runtime/issues/68837</Issue>
-        </ExcludeList>
-        <ExcludeList Include = "$(XunitTestBinBase)/JIT/Stress/ABI/tailcalls_do/**">
-            <Issue>https://github.com/dotnet/runtime/issues/68837</Issue>
-        </ExcludeList>
-        <ExcludeList Include = "$(XunitTestBinBase)/JIT/Stress/ABI/pinvokes_d/**">
-            <Issue>https://github.com/dotnet/runtime/issues/68837</Issue>
-        </ExcludeList>
-        <ExcludeList Include = "$(XunitTestBinBase)/JIT/Stress/ABI/pinvokes_do/**">
-            <Issue>https://github.com/dotnet/runtime/issues/68837</Issue>
-        </ExcludeList>
         <ExcludeList Include="$(XunitTestBinBase)/profiler/multiple/multiple/*">
             <Issue>https://github.com/dotnet/runtime/issues/57875</Issue>
         </ExcludeList>