diff --git a/src/libraries/System.Memory/tests/Span/IndexOfAnyValues.cs b/src/libraries/System.Memory/tests/Span/IndexOfAnyValues.cs
index 843619a4274155..4ca29be532888d 100644
--- a/src/libraries/System.Memory/tests/Span/IndexOfAnyValues.cs
+++ b/src/libraries/System.Memory/tests/Span/IndexOfAnyValues.cs
@@ -198,6 +198,7 @@ static void Test<T>(ReadOnlySpan<T> needle, IndexOfAnyValues<T> values) where T
 
         [Theory]
         [MemberData(nameof(Values_MemberData))]
+        [ActiveIssue("https://github.com/dotnet/runtime/issues/80875", TestPlatforms.iOS | TestPlatforms.tvOS)]
         public static void IndexOfAnyValues_GetValues(string needle, byte[] byteNeedle)
         {
             char[] charValuesActual = s_getValuesCharMethod(IndexOfAnyValues.Create(needle));
diff --git a/src/libraries/System.Numerics.Vectors/tests/Matrix4x4Tests.cs b/src/libraries/System.Numerics.Vectors/tests/Matrix4x4Tests.cs
index 0aacc92730f1f4..be828eacfc9383 100644
--- a/src/libraries/System.Numerics.Vectors/tests/Matrix4x4Tests.cs
+++ b/src/libraries/System.Numerics.Vectors/tests/Matrix4x4Tests.cs
@@ -76,6 +76,7 @@ public void Matrix4x4IndexerGetTest(float m11, float m12, float m13, float m14,
         [InlineData(1.0f, 0.0f, 1.0f, 0.0f, 1.0f, 0.0f, 1.0f, 0.0f, 1.0f, 0.0f, 1.0f, 0.0f, 1.0f, 0.0f, 1.0f, 0.0f)]
         [InlineData(3.1434343f, 1.1234123f, 0.1234123f, -0.1234123f, 3.1434343f, 1.1234123f, 3.1434343f, 1.1234123f, 0.1234123f, -0.1234123f, 3.1434343f, 1.1234123f, 3.1434343f, 1.1234123f, 0.1234123f, -0.1234123f)]
         [InlineData(1.0000001f, 0.0000001f, 2.0000001f, 0.0000002f, 1.0000001f, 0.0000001f, 1.0000001f, 0.0000001f, 2.0000001f, 0.0000002f, 1.0000001f, 0.0000001f, 1.0000001f, 0.0000001f, 2.0000001f, 0.0000002f)]
+        [ActiveIssue("https://github.com/dotnet/runtime/issues/80876", TestPlatforms.iOS | TestPlatforms.tvOS)]
         public void Matrix4x4IndexerSetTest(float m11, float m12, float m13, float m14, float m21, float m22, float m23, float m24, float m31, float m32, float m33, float m34, float m41, float m42, float m43, float m44)
         {
             var matrix = new Matrix4x4(0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f, 0.0f);