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2 stars written in Cython
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Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtool…

Cython 900 297 Updated Jul 19, 2026

💥 Cython memory pool for RAII-style memory management

Cython 461 33 Updated Mar 27, 2026