diff --git a/src/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.csproj b/src/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.csproj
index 01cfa35bb3..753152a182 100644
--- a/src/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.csproj
+++ b/src/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.csproj
@@ -1,4 +1,5 @@
 <Project Sdk="Microsoft.NET.Sdk">
+
   <PropertyGroup>
     <!-- OmniSharp/VS Code requires TargetFrameworks to be in descending order for IntelliSense and analysis. -->
     <TargetFrameworks>$(NetFrameworkMinimumSupportedVersion)</TargetFrameworks>
@@ -7,8 +8,8 @@
     <MinVerTagPrefix>Instrumentation.AspNet-</MinVerTagPrefix>
   </PropertyGroup>
 
-  <!--Do not run Package Baseline Validation as this package has never released a stable version.
-  Remove this property once we have released a stable version and add PackageValidationBaselineVersion property.-->
+  <!-- Do not run Package Baseline Validation as this package has never released a stable version.
+  Remove this property once we have released a stable version and add PackageValidationBaselineVersion property. -->
   <PropertyGroup>
     <DisablePackageBaselineValidation>true</DisablePackageBaselineValidation>
   </PropertyGroup>
@@ -31,4 +32,5 @@
   <ItemGroup>
     <PackageReference Include="OpenTelemetry.Api" Version="$(OpenTelemetryCoreLatestVersion)" />
   </ItemGroup>
+
 </Project>
diff --git a/src/OpenTelemetry.Instrumentation.AspNet/OpenTelemetry.Instrumentation.AspNet.csproj b/src/OpenTelemetry.Instrumentation.AspNet/OpenTelemetry.Instrumentation.AspNet.csproj
index db66f84a14..c21ef4a406 100644
--- a/src/OpenTelemetry.Instrumentation.AspNet/OpenTelemetry.Instrumentation.AspNet.csproj
+++ b/src/OpenTelemetry.Instrumentation.AspNet/OpenTelemetry.Instrumentation.AspNet.csproj
@@ -1,15 +1,16 @@
 <Project Sdk="Microsoft.NET.Sdk">
+
   <PropertyGroup>
     <!-- OmniSharp/VS Code requires TargetFrameworks to be in descending order for IntelliSense and analysis. -->
     <TargetFrameworks>$(NetFrameworkMinimumSupportedVersion)</TargetFrameworks>
-    <Description>ASP.NET instrumentation for OpenTelemetry .NET</Description>
+    <Description>ASP.NET instrumentation for OpenTelemetry .NET.</Description>
     <PackageTags>$(PackageTags);distributed-tracing;AspNet;MVC;WebAPI</PackageTags>
     <IncludeInstrumentationHelpers>true</IncludeInstrumentationHelpers>
     <MinVerTagPrefix>Instrumentation.AspNet-</MinVerTagPrefix>
   </PropertyGroup>
 
-  <!--Do not run Package Baseline Validation as this package has never released a stable version.
-  Remove this property once we have released a stable version and add PackageValidationBaselineVersion property.-->
+  <!-- Do not run Package Baseline Validation as this package has never released a stable version.
+  Remove this property once we have released a stable version and add PackageValidationBaselineVersion property. -->
   <PropertyGroup>
     <DisablePackageBaselineValidation>true</DisablePackageBaselineValidation>
   </PropertyGroup>
diff --git a/src/OpenTelemetry.Instrumentation.AspNetCore/CHANGELOG.md b/src/OpenTelemetry.Instrumentation.AspNetCore/CHANGELOG.md
index 1567f79401..be111b2388 100644
--- a/src/OpenTelemetry.Instrumentation.AspNetCore/CHANGELOG.md
+++ b/src/OpenTelemetry.Instrumentation.AspNetCore/CHANGELOG.md
@@ -2,6 +2,9 @@
 
 ## Unreleased
 
+* Drop support for .NET 6 as this target is no longer supported.
+  ([#2138](https://github.com/open-telemetry/opentelemetry-dotnet-contrib/pull/2138))
+
 ## 1.9.0
 
 Released 2024-Jun-17
diff --git a/src/OpenTelemetry.Instrumentation.AspNetCore/OpenTelemetry.Instrumentation.AspNetCore.csproj b/src/OpenTelemetry.Instrumentation.AspNetCore/OpenTelemetry.Instrumentation.AspNetCore.csproj
index a95693ee5a..0f5087d0f1 100644
--- a/src/OpenTelemetry.Instrumentation.AspNetCore/OpenTelemetry.Instrumentation.AspNetCore.csproj
+++ b/src/OpenTelemetry.Instrumentation.AspNetCore/OpenTelemetry.Instrumentation.AspNetCore.csproj
@@ -1,7 +1,8 @@
 <Project Sdk="Microsoft.NET.Sdk">
+
   <PropertyGroup>
     <!-- OmniSharp/VS Code requires TargetFrameworks to be in descending order for IntelliSense and analysis. -->
-    <TargetFrameworks>net8.0;net6.0;netstandard2.0</TargetFrameworks>
+    <TargetFrameworks>net8.0;$(NetStandardMinimumSupportedVersion)</TargetFrameworks>
     <Description>ASP.NET Core instrumentation for OpenTelemetry .NET</Description>
     <PackageTags>$(PackageTags);distributed-tracing;AspNetCore</PackageTags>
     <MinVerTagPrefix>Instrumentation.AspNetCore-</MinVerTagPrefix>
diff --git a/test/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.Tests/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.Tests.csproj b/test/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.Tests/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.Tests.csproj
index 88d63d331b..526236c90d 100644
--- a/test/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.Tests/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.Tests.csproj
+++ b/test/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.Tests/OpenTelemetry.Instrumentation.AspNet.TelemetryHttpModule.Tests.csproj
@@ -1,8 +1,9 @@
 <Project Sdk="Microsoft.NET.Sdk">
+
   <PropertyGroup>
-    <Description>Unit test project for ASP.NET HttpModule</Description>
     <!-- OmniSharp/VS Code requires TargetFrameworks to be in descending order for IntelliSense and analysis. -->
     <TargetFrameworks>$(NetFrameworkMinimumSupportedVersion)</TargetFrameworks>
+    <Description>Unit test project for ASP.NET HttpModule.</Description>
   </PropertyGroup>
 
   <ItemGroup>
@@ -26,4 +27,5 @@
       <Link>Resources\web.config.uninstall.xdt</Link>
     </EmbeddedResource>
   </ItemGroup>
+
 </Project>
diff --git a/test/OpenTelemetry.Instrumentation.AspNet.Tests/OpenTelemetry.Instrumentation.AspNet.Tests.csproj b/test/OpenTelemetry.Instrumentation.AspNet.Tests/OpenTelemetry.Instrumentation.AspNet.Tests.csproj
index bb0d66597d..e0fd3fe7a6 100644
--- a/test/OpenTelemetry.Instrumentation.AspNet.Tests/OpenTelemetry.Instrumentation.AspNet.Tests.csproj
+++ b/test/OpenTelemetry.Instrumentation.AspNet.Tests/OpenTelemetry.Instrumentation.AspNet.Tests.csproj
@@ -1,8 +1,9 @@
 <Project Sdk="Microsoft.NET.Sdk">
+
   <PropertyGroup>
-    <Description>Unit test project for OpenTelemetry ASP.NET instrumentation</Description>
     <!-- OmniSharp/VS Code requires TargetFrameworks to be in descending order for IntelliSense and analysis. -->
     <TargetFrameworks>$(NetFrameworkMinimumSupportedVersion)</TargetFrameworks>
+    <Description>Unit test project for OpenTelemetry ASP.NET instrumentation.</Description>
   </PropertyGroup>
 
   <ItemGroup>
diff --git a/test/OpenTelemetry.Instrumentation.AspNetCore.Benchmarks/OpenTelemetry.Instrumentation.AspNetCore.Benchmarks.csproj b/test/OpenTelemetry.Instrumentation.AspNetCore.Benchmarks/OpenTelemetry.Instrumentation.AspNetCore.Benchmarks.csproj
index 23c4731175..7d0cb435f8 100644
--- a/test/OpenTelemetry.Instrumentation.AspNetCore.Benchmarks/OpenTelemetry.Instrumentation.AspNetCore.Benchmarks.csproj
+++ b/test/OpenTelemetry.Instrumentation.AspNetCore.Benchmarks/OpenTelemetry.Instrumentation.AspNetCore.Benchmarks.csproj
@@ -1,13 +1,16 @@
 <Project Sdk="Microsoft.NET.Sdk">
+
   <PropertyGroup>
-    <OutputType>Exe</OutputType>
     <!-- OmniSharp/VS Code requires TargetFrameworks to be in descending order for IntelliSense and analysis. -->
-    <TargetFrameworks>$(SupportedNetTargets)</TargetFrameworks>
+    <TargetFrameworks>$(SupportedNetTargetsWithoutNet6)</TargetFrameworks>
+    <OutputType>Exe</OutputType>
   </PropertyGroup>
 
   <ItemGroup>
     <FrameworkReference Include="Microsoft.AspNetCore.App" />
+  </ItemGroup>
 
+  <ItemGroup>
     <PackageReference Include="BenchmarkDotNet" Version="$(BenchmarkDotNetPkgVer)" />
     <PackageReference Include="OpenTelemetry.Exporter.InMemory" Version="$(OpenTelemetryExporterInMemoryPkgVer)" />
   </ItemGroup>
diff --git a/test/OpenTelemetry.Instrumentation.AspNetCore.Tests/OpenTelemetry.Instrumentation.AspNetCore.Tests.csproj b/test/OpenTelemetry.Instrumentation.AspNetCore.Tests/OpenTelemetry.Instrumentation.AspNetCore.Tests.csproj
index 004daa67a8..dd8ec60246 100644
--- a/test/OpenTelemetry.Instrumentation.AspNetCore.Tests/OpenTelemetry.Instrumentation.AspNetCore.Tests.csproj
+++ b/test/OpenTelemetry.Instrumentation.AspNetCore.Tests/OpenTelemetry.Instrumentation.AspNetCore.Tests.csproj
@@ -1,14 +1,10 @@
 <Project Sdk="Microsoft.NET.Sdk">
+
   <PropertyGroup>
-    <Description>Unit test project for OpenTelemetry ASP.NET Core instrumentation</Description>
-    <TargetFrameworks>$(SupportedNetTargets)</TargetFrameworks>
+    <TargetFrameworks>$(SupportedNetTargetsWithoutNet6)</TargetFrameworks>
+    <Description>Unit test project for OpenTelemetry ASP.NET Core instrumentation.</Description>
   </PropertyGroup>
 
-  <ItemGroup Condition="'$(TargetFramework)' == 'net6.0'" >
-    <PackageReference Include="Microsoft.AspNetCore.Mvc.Razor.RuntimeCompilation" Version="6.0.33" />
-    <PackageReference Include="Microsoft.AspNetCore.Mvc.Testing" Version="6.0.33"/>
-  </ItemGroup>
-
   <ItemGroup Condition="'$(TargetFramework)' == 'net8.0'" >
     <PackageReference Include="Microsoft.AspNetCore.Mvc.Razor.RuntimeCompilation" Version="8.0.8" />
     <PackageReference Include="Microsoft.AspNetCore.Mvc.Testing" Version="8.0.8"/>
@@ -37,4 +33,5 @@
       <CopyToOutputDirectory>Always</CopyToOutputDirectory>
     </EmbeddedResource>
   </ItemGroup>
+
 </Project>